Hey monkeyc, I could pretty much repeat Darkestlight's post. My mom, who thought she had depression, but I think had bipolar, was off and on Effexor for years which really helped her with the depression. Effexor is regularly used in the treatment of alcohol dependency because it addresses anxiety and depression. Effexor is not generally prescribed for bipolar disorder, as both manic and hypomanic episodes may result. Effexor (venlafaxine) is approved for the treatment of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), panic disorder, and social anxiety disorder (social phobia). Effexor may. User Reviews for Venlafaxine to treat Bipolar Disorder. Also known as: Effexor XR. The following information is NOT intended to endorse drugs or recommend therapy. Obviously, this is very important for bipolar patients to watch for. Other Important Facts These facts may be important to be aware of if you're taking or plan to take Effexor. What other drugs will affect Effexor? Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking Effexor with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Effexor XR is prescribed for the treatment of and panic disorder in adults. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this medication. The treatment was very successful. In 2005 I began treatment for Bipolar Disorder, severe major depression and Post Traumatic Stress Disorder. I am currently taking the following medications: Effexor XR (750 mg.), Seroquel (550 mg.), Lorazapam (1 mg.). Effexor is taken for treating Bipolar Disorder. 8,274 patients conversations about taking Effexor for Bipolar Disorder, rating Effexor 2.1712785930999137 out of 5 for helping in treatment of Bipolar Disorder.